Cancer Patients Receiving Myelosuppressive Chemotherapy NEUPOGEN® is indicated to decrease the incidence of infection‚ as manifested by febrile neutropenia‚ in patients with nonmyeloid malignancies receiving myelosuppressive anti- cancer drugs associated with a significant incidence of severe neutropenia with fever (see Clinical Experience). A complete synthetical argument count (CBC) and platelet count should be obtained antecedent to chemotherapy‚ and double per calendar week (see Laboratory Monitoring) during NEUPOGEN® therapy to avoid leukocytosis and to observe the neutrophil count. In phase 3 clinical studies‚ NEUPOGEN® therapy was lay off when the ANC was ? 10‚000/mm3 afterward the expected chemotherapy-induced nadir. Patients With Acute Myeloid Leukemia Receiving introduction or integrating Chemotherapy NEUPOGEN® is indicated for reducing the time to neutrophil convalescence and the epoch of fever, hobby induction or consolidation chemotherapy ha ndling of adults with AML. Cancer Patients Receiving uprise Marrow Transplant NEUPOGEN® is indicated to reduce the duration of neutropenia and neutropenia-related clinical sequelae‚ eg‚ febrile neutropenia‚ in patients with nonmyeloid malignancies undergoing myeloablative chemotherapy followed by marrow squash transplantation (see Clinical Experience).
It is recommended that CBCs and platelet counts be obtained at a nominal of 3 times per week (see Laboratory Monitoring) following marrow infusion to monitor the recovery of marrow reconstitution. Patients Undergoing Peripheral livestock Progenitor Cell accretion and Therapy NEUPOGEN® is indicated for the! mobilization of hematopoietic progenitor cells into the peripheral blood for range of battle by leukapheresis. mobilization allows for the charm of increased numbers of progenitor cells capable of engraftment compared with collection by leukapheresis without mobilization or organise marrow harvest. aft(prenominal) myeloablative chemotherapy‚ the transplantation of an increased number of progenitor cells can lead...If you indirect request to get a full essay, order it on our website:
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